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Product Information:

3013618-84-0

SGI-1776-VHL-02 is a stereoselective PIM PROTAC degrader. SGI-1776-VHL-02 promotes the ubiquitination and degradation of PIM1, PIM2 and PIM3. SGI-1776-VHL-02 downregulates c-myc protein levels, induces Apoptosis. SGI-1776-VHL-02 has anti-cancer activity against prostate cancer. SGI-1776-VHL-02 can be used in studies related to prostate cancer.

Cat. No.: EX-A12141    Purity: >98%
Chemical
Chemical structure of 3013618-84-0


For research only, Do not use for Human!

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CAS No.3013618-84-0
Purity>98%
FormulaC50H62F3N9O6S
Mol Weight974.144
ColorWhite to off-white
StateSolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Torres-Ayuso P, et al. PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer. Cell Chem Biol. 2024;31(2):326-337.e11.

CoACoA of 3013618-84-0

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