1H-Benzimidazole-6-carboxylic acid, 2-[[4-[6-[[2-fluoro-4-(3-oxetanyl)phenyl]methoxy]-2-pyridinyl]-1-piperidinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-

DD202-114 is a potent and selective GLP1R agonist. DD202-114 inhibits hERG with an IC50 of 15.9 μM. DD202-114 exhibits strong CYP2C8 inhibition with an IC50 of 0.22 μM. DD202-114 promotes cAMP accumulation. DD202-114 reduces blood glucose levels and food intake. DD202-114 has the potential to be used in the study of type 2 diabetes mellitus (T2DM) and obesity .


Cat. No.: EX-A10041	Purity: >98%

	Chemical structure of 1H-Benzimidazole-6-carboxylic acid, 2-[[4-[6-[[2-fluoro-4-(3-oxetanyl)phenyl]methoxy]-2-pyridinyl]-1-piperidinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
1g	get quote	Inquire

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


Synonyms	DD202-114/GLP-1 receptor agonist
CAS No.	2886728-09-0
Purity	>98%
Formula	C33H35FN4O5
Mol Weight	586.6532
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhang Z, et al. Design and Evaluation of 3-Phenyloxetane Derivative Agonists of the Glucagon-Like Peptide-1 Receptor. J Med Chem. 2024 Sep 12;67(17):14820-14839. [2]. Dong G, et al. Discovery and Evaluation of DA-302168S as an Efficacious Oral Small-Molecule Glucagon-Like Peptide-1 Receptor Agonist. J Med Chem. 2025 May 8;68(9):9555-9583.
CoA	CoA of 1H-Benzimidazole-6-carboxylic acid, 2-[[4-[6-[[2-fluoro-4-(3-oxetanyl)phenyl]methoxy]-2-pyridinyl]-1-piperidinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-

Smiles:	C(N1C=2C(N=C1CN3CCC(CC3)C=4N=C(OCC5=C(F)C=C(C=C5)C6COC6)C=CC4)=CC=C(C(O)=O)C2)[C@@H]7CCO7

KEYWORDS: buy 1H-Benzimidazole-6-carboxylic acid, 2-[[4-[6-[[2-fluoro-4-(3-oxetanyl)phenyl]methoxy]-2-pyridinyl]-1-piperidinyl]methyl]-1-[(2S)-2-oxetanylmethyl]- | 1H-Benzimidazole-6-carboxylic acid, 2-[[4-[6-[[2-fluoro-4-(3-oxetanyl)phenyl]methoxy]-2-pyridinyl]-1-piperidinyl]methyl]-1-[(2S)-2-oxetanylmethyl]- supplier | purchase | cost | manufacturer | order | distributor | buy 2886728-09-0 | 2886728-09-0 supplier


		Search