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Product Information:

1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-8-fluoro-4-hydroxy-10-(4-hydroxybutyl)-9-methyl-, (4S)-

Hydrotecan is a Camptothecin derivative that can be used as an ADC cytotoxin. Hydrotecan can be used to synthesize ADC molecules.

Cat. No.: EX-A13092    Purity: >98%
Chemical
Chemical structure of 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-8-fluoro-4-hydroxy-10-(4-hydroxybutyl)-9-methyl-, (4S)-


For research only, Do not use for Human!

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CAS No.2694026-68-9
Purity>98%
FormulaC25H25FN2O5
Mol Weight452.4748
ColorOff-white to yellow
StateSolid
SolubilityDMSO : ? 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, sealed storage, away from moisture. In solvent -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Wei Li, et al. Auristatin derivatives and conjugates thereof. WO2024023735A1.

CoACoA of 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-8-fluoro-4-hydroxy-10-(4-hydroxybutyl)-9-methyl-, (4S)-
Smiles:C(C)[C@]1(O)C2=C(C(=O)N3C(=C2)C=4C(C3)=CC=5C(N4)=CC(F)=C(C)C5CCCCO)COC1=O

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