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Product Information:

6,7,12,13-Tetrahydro-3-hydroxy-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one

Rho-associated protein kinase, ROCK2 (2)

Cat. No.: EX-A8420    Purity: >98%
Chemical
Chemical structure of 6,7,12,13-Tetrahydro-3-hydroxy-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one


For research only, Do not use for Human!

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CAS No.2226941-26-8
Purity>98%
FormulaC20H13N3O2
Mol Weight327.3361
ColorOff-white to gray
Statesolid powder
SolubilityDMSO : 125 mg/mL
Shelf Life>1 years if stored properly
Storage4°C, sealed storage, away from moisture and light
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Wang J, et, al. Discovery of unglycosylated indolocarbazoles as ROCK2 isoform-selective inhibitors for the treatment of breast cancer metastasis. Eur J Med Chem. 2023 Mar 15;250:115181.

CoACoA of 6,7,12,13-Tetrahydro-3-hydroxy-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one
Smiles:O=C1NCC2=C1C3=C(C4=C2C5=C(N4)C=CC=C5)NC6=C3C=C(O)C=C6

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