20-HETE inhibitor-2

20-HETE inhibitor-2 is an orally active 20-HETE inhibitor. 20-HETE inhibitor-2 can inhibit the activities of CYP4F2 and CYP4A11, thereby suppressing the production of 20-HETE. 20-HETE inhibitor-2 has the effect of improving blood glucose and can be used for the research of various diseases related to 20-HETE such as obesity .


Cat. No.: EX-A9650	Purity: >98%

	Chemical structure of 20-HETE inhibitor-2

For research only, Do not use for Human!

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CAS No.	2992666-48-3
Purity	>98%
Formula	C19H23FN4O
Mol Weight	342.4105
Color	White to off-white
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lee Apostle Mcdermott, et al. 20-hete formation inhibitors. US, WO2020163689. 2020-02-07. [2]. Xiong C, et al. 1,4-diheterocyclic substituted aromatic ring or aromatic heterocyclic compound and use thereof. WO2023185821A1. 2023-10-05.
CoA	CoA of 20-HETE inhibitor-2

Smiles:	O=C1N(CCC1)CC2CCN(C=3C=CC(=CC3F)C=4C=NNC4)CC2


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