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Product Information:

1Z105

1Z105 is an oral active TLR4/MD2 ligand. 1Z105 enhances dendritic cell maturation and antigen presentation and prevents rthritis.

Cat. No.: EX-A13177    Purity: >98%
Chemical
Chemical structure of 1Z105


For research only, Do not use for Human!

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CAS No.1438280-73-9
Purity>98%
FormulaC25H26N4O2S
Mol Weight446.565
ColorWhite to off-white
StateSolid
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years; In solvent -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Goff PH, et al. Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses. J Virol. 2015;89(6):3221-3235.

[2]. Hayashi T, et al. Novel synthetic toll-like receptor 4/MD2 ligands attenuate sterile inflammation. J Pharmacol Exp Ther. 2014;350(2):330-340.

CoACoA of 1Z105
Smiles:O=C1C2=C(N=C(SCC(=O)NC3CCCCC3)N1C=4C=CC=CC4)C=5C=CC=CC5N2C

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