1S,3R-RSL-3

RSL3 is an inhibitor of glutathione peroxidase 4 (GPX4), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell.


Cat. No.: EX-A1392	Purity: >98%

	Chemical structure of 1S,3R-RSL-3

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	485	In-stock
500mg	685	In-stock
1g	985	In-stock
5g	2350	In-stock

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Synonyms	RSL-3
Synonyms 2	(1S,3R)-RSL-3
CAS No.	1219810-16-8
Purity	>98%
Formula	C23H21ClN2O5
Mol Weight	440.876
Color	white to off-white
State	powder
Solubility	DMSO >100mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Shin D, et al. Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer. Free Radic Biol Med. 2018 Dec;129:454-462.
CoA	CoA of 1S,3R-RSL-3

Smiles:	COC(=O)[C@H]1CC2=C(NC3=C2C=CC=C3)[C@@H](N1C(=O)CCl)C1=CC=C(C=C1)C(=O)OC


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