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Product Information:

(1R,2R)-ML-SI3

(1R,2R)-ML-SI3 is a potent inhibitor of both TRPML1 and TRPML2 (IC50 values of 1.6 and 2.3 μM) and a weak inhibitor (IC50 12.5 μM) of TRPML3.

Cat. No.: EX-A6408    Purity: >98%
Chemical
Chemical structure of (1R,2R)-ML-SI3


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg685In-stock
50mg985In-stock
100mg1550In-stock
200mg2385In-stock
500mgget quoteIn-stock
1gget quoteIn-stock


Synonyms(-)-trans-ML-SI3
Synonyms 2(1R,2R)-ML-SI3
CAS No.2418594-00-8
Purity>98%
FormulaC23H31N3O3S
Mol Weight429.576
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Leser C, Keller M, Gerndt S, et al. Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3. Eur J Med Chem. 2021;210:112966.

CoACoA of (1R,2R)-ML-SI3

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