1G244

1G244 is a potent DPP8/9 inhibitor with IC50s of 12 nM and 84 nM, respectively. 1G244 does not inhibit DPPIV and DPPII. 1G244 induces apoptosis in multiple myeloma cells and has anti-myeloma effects.


Cat. No.: EX-A5091	Purity: >98%

	Chemical structure of 1G244

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	585	In-stock
100mg	785	In-stock
250mg	1385	In-stock

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CAS No.	847928-32-9
Purity	>98%
Formula	C29H30F2N4O2
Mol Weight	504.5709
Color	Off-white to light yellow
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -4°C, sealed storage, away from moisture and light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sato T, et al. DPP8 is a novel therapeutic target for multiple myeloma. Sci Rep. 2019 Dec 2;9(1):18094. [2]. Leen Heirbaut, et al. Probing for improved selectivity with dipeptidederived inhibitors of dipeptidyl peptidases 8 and 9: the impact of P1-variation. MedChemComm. 2016, 7.
CoA	CoA of 1G244

Smiles:	O=C(N1CC2=C(C=CC=C2)C1)[C@@H](N)CC(N3CCN(C(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5)CC3)=O


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