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Product Information:

10-Cl-BBQ

10-Cl-BBQ is a high affinity AhR ligand with immunosuppressive activity. 10-Cl-BBQ promotes cytosol to nuclear translocation of AhR and activates the AhR-regulated reporter gene at nanomolar concentrations .

Cat. No.: EX-A7259    Purity: >98%
Chemical
Chemical structure of 10-Cl-BBQ


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg800In-stock
500mg1500In-stock
1g2400In-stock
5gget quoteIn-stock


CAS No.23982-76-5
Purity>98%
FormulaC18H9ClN2O
Mol Weight304.73
Colorlight yellow to yellow
Statesolid powder
SolubilityDMSO : 1.6 mg/mL (5.48 mM; ultrasonic and warming and heat to 60?; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Shelf Life>3 years if stored properly
StoragePowder -20℃ sealed storage, away from moisture and light, 3 years ; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sumit Punj, et al. Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease. PLoS One. 2014 Feb 19;9(2):e88726.

[2]. Allison K Ehrlich, et al. Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice. J Immunol. 2016 Jan 1;196(1):264-73.

CoACoA of 10-Cl-BBQ

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