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Product Information:

10,11-Dehydrocurvularin

10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity .

Cat. No.: EX-A10620    Purity: >98%
Chemical
Chemical structure of 10,11-Dehydrocurvularin


For research only, Do not use for Human!

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CAS No.21178-57-4
Purity>98%
FormulaC16H18O5
Mol Weight290.3111
ColorWhite to light yellow
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Xu Y, et al. Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus. Appl Environ Microbiol. 2013 Mar;79(6):2038-47.

[2]. Cochrane RV, et al. Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs. Chembiochem. 2015 Nov;16(17):2479-83.

CoACoA of 10,11-Dehydrocurvularin
Smiles:OC1=C(C(/C=C/CCC[C@@H]2C)=O)C(CC(O2)=O)=CC(O)=C1

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