ICG-001

ICG-001 is an inhibitor of β-catenin/TCF mediated transcription and specifically binding to cyclic AMP response element-binding protein with an IC50 of 3 μM.


Cat. No.: EX-A1745	Purity: >98%

	Chemical structure of ICG-001

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	585	In-stock
500mg	800	In-stock
1g	1200	In-stock
2g	1900	In-stock
5g	3800	In-stock
10g	5760	In-stock

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


CAS No.	847591-62-2
Purity	>98%
Formula	C33H32N4O4
Mol Weight	548.6316
Appearance	White to off-white solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Yan D, et al, Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways. J Biol Chem, 2012, 287(11), 8598-8612. [2]. Henderson WR Jr, et al, Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci USA, 2010, 107(32), 14309-14314. [3]. Emami KH, et al. A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]. Proc Natl Acad Sci USA, 2004, 101(34), 12682-12687. [4]. Liu Y, et al. ICG-001 suppresses growth of gastric cancer cells and reduces chemoresistance of cancer stem cell-like population. J Exp Clin Cancer Res. 2017 Sep 11;36(1):125.
CoA	CoA of ICG-001

Smiles:	[H][C@]12CN(CC3=C4C=CC=CC4=CC=C3)C(=O)[C@H](CC3=CC=C(O)C=C3)N1C(=O)CCN2C(=O)NCC1=CC=CC=C1


		Search