Product Information:
Cat. No.: EX-A1681 | Purity: >98% |
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Synonyms | Imaradenant |
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Synonyms 2 | HTL1071 |
CAS No. | 1321514-06-0 |
Purity | >98% |
Formula | C15H11ClFN5 |
Mol Weight | 315.733 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Jazayeri A, Andrews SP, Marshall FH. Structurally Enabled Discovery of Adenosine A(2A) Receptor Antagonists. Chem Rev. 2017 Jan 11;117(1):21-37. doi:10.1021/acs.chemrev.6b00119. Epub 2016 Jun 22. Review. PubMed PMID: 27333206. [2]. Alexandra Borodovsky, et al. Preclinical pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression. AACR Cancer Res. 2017, 77(13 Suppl):Abstract nr 5580. |
CoA | CoA of AZD-4635 |
Smiles: | CC1=CC(=CC(Cl)=N1)C1=C(N=C(N)N=N1)C1=CC=C(F)C=C1 |
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