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Product Information:

RG7112

RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor with HTRF IC50 of 18 nM.

Cat. No.: EX-A1686    Purity: >98%
RG7112
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg1800In-stock
1g2600In-stock
5g9500In-stock


SynonymsRO5045337
CAS No.939981-39-2
Purity>98%
FormulaC38H48Cl2N4O4S
Mol Weight727.783
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Vu B, et al. Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development. ACS Med Chem Lett. 2013, 4(5):466-9.
CoACoA of RG7112
Smiles:CCOC1=CC(=CC=C1C1=N[C@@](C)(C2=CC=C(Cl)C=C2)[C@](C)(N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1)C1=CC=C(Cl)C=C1)C(C)(C)C

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