Lanifibranor

Lanifibranor is a pan peroxisome proliferator-activated receptor (PPAR) agonist with EC50s of 1.5, 0.87 and 0.21 μM for human PPARα, PPARσ and PPARγ, respectively.


Cat. No.: EX-A1511	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	450	In-stock
500mg	650	In-stock
1g	950	In-stock
2g	1550	In-stock
5g	2925	In-stock
10g	4585	In-stock

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Synonyms	IVA337
CAS No.	927961-18-0
Purity	>98%
Formula	C19H15ClN2O4S2
Mol Weight	434.916
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Boubia B, et al. Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) α/γ/δ Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate. J Med Chem. 2018 Feb 27. [2]. Ruzehaji N, et al. Pan PPAR agonist IVA337 is effective in prevention and treatment of experimental skin fibrosis. Ann Rheum Dis. 2016 Dec;75(12):2175-2183.
CoA	CoA of Lanifibranor

Smiles:	OC(=O)CCCC1=CC2=C(C=CC(Cl)=C2)N1S(=O)(=O)C1=CC=C2N=CSC2=C1


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