Setipiprant

Setipiprant (ACT-129968) is an orally active and selective CRTH2 antagonist. Setipiprant interacts with hCRTH2 receptor with an IC50 value of 6 nM. Setipiprant inhibits prostanoid receptors hDP1 and hEP2 with IC50 values of 1290 and 2600 nM, respectively.


Cat. No.: EX-A1767	Purity: >99%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	485	In-stock
500mg	650	In-stock
1g	950	In-stock
5g	2285	In-stock
10g	3785	In-stock

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Synonyms	ACT-129968
Synonyms 2	KYTH-105
CAS No.	866460-33-5
Purity	>99%
Formula	C24H19FN2O3
Mol Weight	402.4177
Appearance	Solid powder
Solubility	DMSO : > 30 mg/mL (89.58 mM)
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Heinz Fretz, et al. Identification of 2 (2-(1-Naphthoyl)-8-fluoro-3,4-dihydro 1H pyrido[4,3 b]indol-5(2H) yl)acetic Acid (Setipiprant/ACT 129968), a Potent, Selective, and Orally Bioavailable Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2) Antagonis. 2013.
CoA	CoA of Setipiprant

Smiles:	OC(=O)CN1C2=C(CN(CC2)C(=O)C2=CC=CC3=CC=CC=C23)C2=C1C=CC(F)=C2


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