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Product Information:

GSK429286A

GSK429286A (RHO-15) is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM, respectively.

Cat. No.: EX-A1119    Purity: >98%
GSK429286A
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg695In-stock
500mg895In-stock
1g1195In-stock
5g3895In-stock
10g6650In-stock


CAS No.864082-47-3
Purity>98%
FormulaC21H16F4N4O2
Mol Weight432.371
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1] Goodman KB, et al. Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors. J Med Chem, 2007, 50(1), 6-9.

[2] Nichols RJ, et al. Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease. Biochem J, 2009, 424(1), 47-60.
CoACoA of GSK429286A
Smiles:CC1=C(C(CC(=O)N1)C1=CC=C(C=C1)C(F)(F)F)C(=O)NC1=CC2=C(NN=C2)C=C1F

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