Inhibitor Specialist 
Product Information:
| Cat. No.: EX-A1534 | Purity: >98% |
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| Size | Unit Price (US$) | Stock | Quantity | Order |
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| Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670 |
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| Synonyms | Bafetinib |
|---|---|
| Synonyms 2 | NS-187 |
| CAS No. | 859212-16-1 |
| Purity | >98% |
| Formula | C30H31F3N8O |
| Mol Weight | 576.6153 |
| Appearance | white to off-white powder |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Kimura S, et al. NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia. Blood. 2005 Dec 1;106(12):3948-3954.
[2]. Yokota A, et al. INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity. Blood. 2007, 109(1), 306-314. |
| CoA | CoA of INNO-406 |
| Smiles: | CN(C)[C@H]1CCN(CC2=C(C=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CN=C3)=C(C)C=C2)C(F)(F)F)C1 |
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