Treprostinil diethanolamine

Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (UT-15C) diethanolamine increases upregulation of cAMP toward maintaining homeostasis within the vasculature. Treprostinil (UT-15C) diethanolamine can result in vasodilatation of human pulmonary arteries.


Cat. No.: EX-A1418	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	650	In-stock
100mg	850	In-stock
200mg	1250	In-stock
500mg	2150	In-stock
1g	3350	In-stock

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


Synonyms	Treprostinil diolamine
Synonyms 2	UT-15C
CAS No.	830354-48-8
Purity	>98%
Formula	C27H45NO7
Mol Weight	495.6487
Appearance	Solid powder
Solubility	DMF: 20 mg/ml,DMSO: 5mg/ml, Ethanol: 13 mg/ml, PBS (pH 7.2): 5 mg/ml
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Whittle BJ, et, al. Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: treprostinil is a potent DP1 and EP2 agonist. Biochem Pharmacol. 2012 Jul 1;84(1):68-75. [2]. Kazemi Z, et, al. Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation. Mol Pharmacol. 2016 Jun;89(6):630-44. [3]. Ghonem N, et, al. Treprostinil, a prostacyclin analog, ameliorates ischemia-reperfusion injury in rat orthotopic liver transplantation. Am J Transplant. 2011 Nov;11(11):2508-16.
CoA	CoA of Treprostinil diethanolamine

Smiles:	OCCNCCO.CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@@H]2CC3=C(C[C@H]12)C=CC=C3OCC(O)=O


		Search