background


Product Information:

FMK

FMK is a an irreversible RSK2 kinase inhibitor, that covalently modifies the C-terminal kinase domain of RSK.

Cat. No.: EX-A846    Purity: >98%
FMK
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg600In-stock
250mg1150In-stock
500mg1700In-stock
1g2400In-stock
2g3900In-stock
5gGet quoteIn-stock


SynonymsRSK2 kinase inhibitor
CAS No.821794-92-7
Purity>98%
FormulaC18H19FN4O2
Mol Weight342.3675
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Cuello F, et al. Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to alpha1-adrenergic stimulation.

[2]. Bain J, et al. The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007 Dec 15;408(3):297-315.

[3]. Kang S, et al. FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. Cancer Cell. 2007 Sep;12(3):187-9.

CoACoA of FMK
Smiles:CC1=CC=C(C=C1)C1=C(N(CCCO)C2=NC=NC(N)=C12)C(=O)CF

KEYWORDS: buy FMK | FMK supplier | purchase | cost | manufacturer | order | distributor | buy 821794-92-7 | 821794-92-7 supplier