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Product Information:

Dinaciclib

Dinaciclib (SCH 727965) is a potent inhibitor of CDK, with IC50s of 1 nM, 1 nM, 3 nM, and 4 nM for CDK2, CDK5, CDK1, and CDK9, respectively.

Cat. No.: EX-A1579    Purity: >98%
Dinaciclib
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg750In-stock
250mg1150In-stock
500mg1650In-stock
1g2350In-stock
5g7600In-stock


SynonymsSCH 727965
CAS No.779353-01-4
Purity>98%
FormulaC21H28N6O2
Mol Weight396.486
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Parry D, et al. Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitor. Mol Cancer Ther. 2010 Aug;9(8):2344-53.

[2]. Feldmann G, et al. Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models. Cancer Biol Ther. 2011 Oct 1;12(7):598-609.

CoACoA of Dinaciclib
Smiles:CCC1=C2N=C(C=C(N(C)C3=C[N+]([O-])=CC=C3)N2N=C1)N1CCCC[C@H]1CCO

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