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Product Information:

AZD2281

Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively.

Cat. No.: EX-A002    Purity: >99%
AZD2281
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg300In-stock
1g450In-stock
2g650In-stock
5g950In-stock
10g1650In-stock


SynonymsOlaparib
CAS No.763113-22-0
Purity>99%
FormulaC24H23FN4O3
Mol Weight434.4628
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Menear KA, et al. 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1. J Med Chem. 2008 Oct 23;51(20):6581-91

CoACoA of AZD2281
Smiles:FC1=CC=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1C(=O)N1CCN(CC1)C(=O)C1CC1

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