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Product Information:

TAK385

Relugolix (TAK-385) is a luteinizing hormone-releasing hormone (LH-RH) receptor antagonist.

Cat. No.: EX-A1083    Purity: >98%
TAK385
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg485In-stock
250mg650In-stock
500mg885In-stock
1g1385In-stock
5g3985In-stock
10g5785In-stock


SynonymsRelugolix
CAS No.737789-87-6
Purity>98%
FormulaC29H27F2N7O5S
Mol Weight623.63
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Miwa K, Hitaka T, Imada T, Sasaki S, Yoshimatsu M, Kusaka M, Tanaka A, Nakata D, Furuya S, Endo S, Hamamura K, Kitazaki T. Discovery of 1-{4-[1-(2,6-difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl )-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea (TAK-385) as a potent, orally active, non-peptide antagonist of the human gonadotropin-releasing hormone receptor. J Med Chem. 2011 Jul 28;54(14):4998-5012. Epub 2011 Jun 23. PubMed PMID: 21657270.
CoACoA of TAK385
Smiles:CONC(=O)NC1=CC=C(C=C1)C1=C(CN(C)C)C2=C(S1)N(CC1=C(F)C=CC=C1F)C(=O)N(C2=O)C1=NN=C(OC)C=C1

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