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Product Information:

Nutlin-3b

Nutlin-3b is a p53/MDM2 inhibitor with an IC50 of 13.6 μM. Nutlin-3b is 150 times less potent in binding to MDM2 than Nutlin-3a.

Cat. No.: EX-A1360    Purity: >98%
Nutlin-3b
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg950In-stock
250mg1700In-stock


CAS No.675576-97-3
Purity>98%
FormulaC30H30Cl2N4O4
Mol Weight581.49
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Vassilev LT, et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science. 2004 Feb 6;303(5659):844-8.

CoACoA of Nutlin-3b
Smiles:COC1=CC=C(C2=N[C@@H]([C@@H](N2C(=O)N2CCNC(=O)C2)C2=CC=C(Cl)C=C2)C2=CC=C(Cl)C=C2)C(OC(C)C)=C1

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