background


Product Information:

Linagliptin

Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.

Cat. No.: EX-A076    Purity: >98%
Linagliptin
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg100In-stock
250mg100In-stock
500mg100In-stock
1g100In-stock
5g300In-stock
10g450In-stock


CAS No.668270-12-0
Purity>98%
FormulaC25H28N8O2
Mol Weight472.5422
AppearanceWhite to off-white solid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Eckhardt M, et al. 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 d

[2]. Thomas L, et al. (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action

[3]. Schurmann C, et al. The dipeptidyl peptidase-4 inhibitor linagliptin attenuates inflammation and accelerates epithelialization in wounds of diabetic ob/ob mice. J Pharmacol Exp Ther. 2012 Jul;342(1):71-80.

[4]. Huan Y, et al. The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo. Sci Rep. 2017 Jun 28;7(1):4351.

CoACoA of Linagliptin
Smiles:CC#CCN1C(=NC2=C1C(=O)N(CC1=NC(C)=C3C=CC=CC3=N1)C(=O)N2C)N1CCC[C@@H](N)C1

KEYWORDS: buy Linagliptin | Linagliptin supplier | purchase | cost | manufacturer | order | distributor | buy 668270-12-0 | 668270-12-0 supplier