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Product Information:

Ansamitocin P-3

Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.

Cat. No.: EX-A492    Purity: >98%
Ansamitocin
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg985In-stock
1g1685In-stock
5g4850In-stock
10g6850In-stock


SynonymsAntibiotic C 15003P3
Synonyms 2Maytansinol isobutyrate
CAS No.66584-72-3
Purity>98%
FormulaC32H43ClN2O9
Mol Weight635.145
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Kiso T, et al. Screening for microtubule-disrupting antifungal agents by using a mitotic-arrest mutant of Aspergillus nidulans and novel action of phenylalanine derivatives accompanying tubulin loss. Antimicrob Agents Chemother. 2004 May;48(5):1739-48

[2]. Venghateri JB, et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at thevinblastine site. PLoS One. 2013 Oct 4;8(10):e75182.
CoACoA of Ansamitocin P-3
Smiles:[H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)C1=C(Cl)C(OC)=CC(C\C(C)=C\C=C\[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)=C1)OC(=O)C(C)C

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