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Product Information:

MC-Val-Cit-PAB-MMAE

MC-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

Cat. No.: EX-A1506    Purity: >98%
MC-Val-Cit-PAB-MMAE
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg700In-stock
250mg1250In-stock
500mg2000In-stock
1g3000In-stock
5gGet quoteIn-stock
10gGet quoteIn-stock


SynonymsVcMMAE
Synonyms 2mc-vc-PAB-MMAE
CAS No.646502-53-6
Purity>98%
FormulaC68H105N11O15
Mol Weight1316.626
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.
CoACoA of MC-Val-Cit-PAB-MMAE
Smiles:CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)C1=CC=CC=C1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCC1=CC=C(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)C=C1)C(C)C

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