Synonyms | Pifithrin-α hydrobromide |
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Synonyms 2 | Pifithrin hydrobromide |
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CAS No. | 63208-82-2 |
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Purity | >98% |
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Formula | C16H19BrN2OS |
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Mol Weight | 367.304 |
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Appearance | solid powder |
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Solubility | Soluble in DMSO |
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Shelf Life | >2 years if stored properly |
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Storage | Powder -20℃ 3 years; In solvent -20℃ 1 month; |
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Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
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Reference: | [1]. Yu W, et al. Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition. Int J Biol Sci. 2016 Jan 1;12(2):198-209.
[2]. Hoagland MS, et al. The p53 Inhibitor Pifithrin-α Is a Potent Agonist of the Aryl Hydrocarbon Receptor. J Pharmacol Exp Ther. 2005 Aug;314(2):603-10.
[3]. Kuang SQ, et al. FOXE3 mutations predispose to thoracic aortic aneurysms and dissections. J Clin Invest. 2016 Mar 1;126(3):948-61. |
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CoA | CoA of Pifithrin-alpha hydrobromide |
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