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Product Information:

Nosiheptide

Nosiheptide is a thiopeptide antibiotic produced by Streptomyces actuosus. Nosiheptide has been widely used as a feed additive for animal growth. Nosiheptide inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core.

Cat. No.: EX-A819    Purity: >98%
Nosiheptide
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg500In-stock
250mg700In-stock
500mg900In-stock
1g1250In-stock
5g3300In-stock
10g5200In-stock


CAS No.56377-79-8
Purity>98%
FormulaC51H43N13O12S6
Mol Weight1222.357
Appearancesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Haste, Nina M et al. “Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus.” The Journal of antibiotics vol. 65,12 (2012): 593-8.

[1]. Yu, Yi et al. “Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework.” ACS chemical biology vol. 4,10 (2009): 855-64.

CoACoA of Nosiheptide
Smiles:C\C=C1/NC(=O)C(NC(=O)C2=CSC(=N2)C2=CC(=O)C(\N=C2C2=CSC(=N2)C2CSC(=O)C3=C(C)C4=C(COC(=O)C(O)CC(NC(=O)C5=CSC1=N5)C1=NC(=CS1)C(=O)N2)C=CC=C4N3)=C1\NC(=CS1)C(=O)NC(=C)C(N)=O)C(C)O

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