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Product Information:

Nutlin-3

Nutlin-3 is a potent and selective p53-MDM2 inhibitor, with Ki of 90 nM.

Cat. No.: EX-A851    Purity: >98%
Nutlin-3
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg365In-stock
250mg525In-stock
500mg685In-stock
1g1000In-stock
5g3300In-stock
10g4960In-stock


CAS No.548472-68-0
Purity>98%
FormulaC30H30Cl2N4O4
Mol Weight581.49
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yu Z, et al. Design, synthesis and biological evaluation of sulfamide and triazole benzodiazepines as novel p53-MDM2 inhibitors. Int J Mol Sci. 2014 Sep 5;15(9):15741-53.

CoACoA of Nutlin-3
Smiles:O=C1NCCN(C(N2[C@@H](C3=CC=C(Cl)C=C3)[C@@H](C4=CC=C(Cl)C=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1

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