Synonyms | (E)-SIS3 |
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Synonyms 2 | SIS3 hydrobromide |
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CAS No. | 521984-48-5 |
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Purity | >98% |
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Formula | C28H28ClN3O3 |
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Mol Weight | 489.993 |
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Appearance | white to off-white powder |
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Solubility | DMSO >20mg/mL |
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Shelf Life | >2 years if stored properly |
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Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
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Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
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Reference: | [1]. Boudreau HE et al. Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells. Br J Cancer. 2014 May 13;110(10):2569-82.
[2]. Jinnin M et al. Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression. Mol Pharmacol. 2006 Feb;69(2):597-607. |
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CoA | CoA of SIS3 |
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