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Product Information:

Maraviroc

Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV.

Cat. No.: EX-A200    Purity: >99%
Maraviroc
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg585In-stock
500mg700In-stock
1g985In-stock
5g2850In-stock
10g4560In-stock


SynonymsUK-427857
CAS No.376348-65-1
Purity>99%
FormulaC29H41F2N5O
Mol Weight513.6655
AppearanceSolid powder
SolubilityDMSO : 50 mg/mL (97.34 mM; Need ultrasonic) Ethanol : 6.5 mg/mL (12.65 mM; Need ultrasonic)
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Dorr P, et al. Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity. Antimicrob Agents Chemother. 2005 Nov;49(11):472

[2]. Mencarelli A, et al. Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis. Sci Rep. 2016 Aug 5;6:30802.

CoACoA of Maraviroc
Smiles:[H][C@]12CC[C@]([H])(CC(C1)N1C(C)=NN=C1C(C)C)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)C1=CC=CC=C1

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