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Product Information:

MAK683

MAK683 is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.

Cat. No.: EX-A1723    Purity: >98%
MAK683
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg525In-stock
100mg700In-stock
250mg1050In-stock
500mg1450In-stock
1g2150In-stock
5g5850In-stock


CAS No.1951408-58-4
Purity>98%
FormulaC20H17FN6O
Mol Weight376.387
AppearanceSolid powder
SolubilityDMSO >50mg/mL; Insoluble in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Chan, Ho Man, et al. TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF. US20160176882 A1.

[2]. Huang D, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21(3):263-271.

CoACoA of MAK683
Smiles:CC1=C(C=CC=N1)C1=CN=C(NCC2=C(F)C=CC3=C2CCO3)N2C=NN=C12

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