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Product Information:

SBI0206965

SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50s of 108 nM for ULK1 kinase and 711 nM for the highly related kinase ULK2.

Cat. No.: EX-A747    Purity: >98%
SBI0206965
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg400In-stock
250mg800In-stock
1g1600In-stock


CAS No.1884220-36-3
Purity>98%
FormulaC21H21BrN4O5
Mol Weight489.319
AppearanceSolid powder
SolubilityDMSO > 100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Lu J, et al. Overexpression of ULK1 Represents a Potential Diagnostic Marker for Clear Cell RenalCarcinoma and the Antitumor Effects of SBI-0206965. EBioMedicine. 2018 Aug;34:85-93.

[2]. Egan DF, et al. Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates. Mol Cell. 2015 Jul 16;59(2):285-97.
CoACoA of SBI0206965
Smiles:CNC(=O)C1=CC=CC=C1OC1=NC(NC2=CC(OC)=C(OC)C(OC)=C2)=NC=C1Br

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