BAY 1895344

Elimusertib (BAY-1895344) is a potent, orally active and selective ATR inhibitor with an IC50 of 7 nM. Elimusertib has anti-tumor activity^[1][2]. Elimusertib can be used for the research of solid tumors and lymphomas^[3].


Cat. No.: EX-A1662	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	400	In-stock
250mg	585	In-stock
500mg	785	In-stock
1g	1000	In-stock
5g	3600	In-stock
10g	5860	In-stock

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Synonyms	Elimusertib
Synonyms 2	BAY-1895344
CAS No.	1876467-74-1
Purity	>98%
Formula	C20H21N7O
Mol Weight	375.427
Appearance	Light yellow to yellow solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Ulrich T. Luecking, et al. Abstract 983: Identification of potent, highly selective and orally available ATR inhibitor BAY 1895344 with favorable PK properties and promising efficacy in monotherapy and combination in preclinical tumor models. Cancer Research. July 2017 Volume 77, Issue 13 Supplement. [2]. Antje Margret Wengner, et al. Abstract 836: ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. Cancer Research. July 2017 Volume 77, Issue 13 Supplement [3]. Ulrich Lücking, et al. Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models. J Med Chem. 2020 Jul 9;63(13):7293-7325.
CoA	CoA of BAY 1895344

Smiles:	C[C@@H]1COCCN1C1=NC2=C(C=CN=C2C2=CC=NN2)C(=C1)C1=CC=NN1C


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