MS023

MS023 is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively.


Cat. No.: EX-A1023	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	585	In-stock
500mg	900	In-stock
1g	1585	In-stock
5g	4650	In-stock
10g	6800	In-stock

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CAS No.	1831110-54-3
Purity	>98%
Formula	C17H25N3O
Mol Weight	287.3999
Appearance	Solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Eram MS, et al. A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. ACS Chem Biol. 2016 Mar 18;11(3):772-81. [2]. Yinghui Zhu, et al. Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia. Blood. 2019 Oct 10;134(15):1257-1268.
CoA	CoA of MS023

Smiles:	CC(C)OC1=CC=C(C=C1)C1=CNC=C1CN(C)CCN


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