Product Information:
Cat. No.: EX-A1067 | Purity: >98% |
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CAS No. | 1801747-42-1 |
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Purity | >98% |
Formula | C16H19Cl2N5 |
Mol Weight | 352.262 |
Appearance | Solid powder |
Solubility | DMSO >10 mg/mL |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Garcia Fortanet J, et al. Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor. J Med Chem. 2016 Sep 8;59(17):7773-82.
[2]. Chen YN, et al. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature. 2016 Jul 7;535(7610):148-52. |
CoA | CoA of SHP099 |
Smiles: | CC1(N)CCN(CC1)C1=CN=C(C(N)=N1)C1=CC=CC(Cl)=C1Cl |
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