background


Product Information:

YY-20394

YY-20394 (Linperlisib, PI3Kδ-IN-2) is a potent and selective PI3Kδ inhibitor. YY-20394 significantly inhibited primary tumor growth in immune-competent mice with 4T1 and CT26 tumors, as well as 4T1 lung metastasis with dose dependency. YY-20394 significantly inhibited T cell differentiation into Treg both in mouse splenocyte and in human primary CD4+ T cells, and was especially potent inhibiting their IL-10 secretion in vitro.

Cat. No.: EX-A1436    Purity: >98%
YY-20394
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg950In-stock
1gget quoteIn-stock
custom sizget quote


SynonymsPI3Kδ-IN-2
Synonyms 2Linperlisib
CAS No.1702816-75-8
Purity>98%
FormulaC28H37FN6O5S
Mol Weight588.694
AppearanceSolid powder
Solubilitysoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. WO 2015055071 A1
CoACoA of YY-20394
Smiles:COC1=C(NS(C)(=O)=O)C=C(C=N1)C1=NC(=NC2=C1C=C(F)C=C2CN1CCC(CC1)C(C)(C)O)N1CCOCC1

KEYWORDS: buy YY-20394 | YY-20394 supplier | purchase | cost | manufacturer | order | distributor | buy 1702816-75-8 | 1702816-75-8 supplier