EPZ020411

EPZ020411 is a selective inhibitor of PRMT6 with an IC50 of 10 nM, has >10 folds selectivity for PRMT6 over PRMT1 and PRMT8. EPZ020411 can be used for the research of cancer.


Cat. No.: EX-A1601	Purity: >98%

	Chemical structure of EPZ020411

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	650	In-stock
50mg	850	In-stock
100mg	1350	In-stock
200mg	2500	In-stock
500mg	3300	In-stock
1g	4500	In-stock

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Synonyms	EPZ020411 HCl salt
CAS No.	1700663-41-7
Purity	>98%
Formula	C25H38N4O3
Mol Weight	442.5942
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mitchell LH, et al. Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 ToolCompound. ACS Med Chem Lett. 2015 Apr 6;6(6):655-659. [2]. He Y, et al. Inhibition of Protein arginine methyltransferase 6 reduces reactive oxygen species production and attenuates aminoglycoside- and cisplatin-induced hair cell death. Theranostics. 2020 Jan 1;10(1):133-150.
CoA	CoA of EPZ020411

Smiles:	CNCCN(C)CC1=CNN=C1C1=CC=C(O[C@H]2C[C@@H](C2)OCCC2CCOCC2)C=C1


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