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Product Information:

AZD3965

AZD3965 is a selective MCT1 inhibitor with a Ki of 1.6 nM, showing 6-fold selectivity over MCT2.

Cat. No.: EX-A806    Purity: >98%
AZD3965
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg675In-stock
250mg1185In-stock
500mg1885In-stock
1g2585In-stock
5g7785In-stock


CAS No.1448671-31-5
Purity>98%
FormulaC21H24F3N5O5S
Mol Weight515.506
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Bola BM, et al. Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport. Mol Cancer Ther. 2014 Dec;13(12):2805-16.

[2]. Polanski R, et al. Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. Clin Cancer Res. 2014 Feb 15;20(4):926-37.

CoACoA of AZD3965
Smiles:CC(C)N1C2=C(C(C(=O)N3C[C@](C)(O)CO3)=C(CC3=C(C)NN=C3C(F)(F)F)S2)C(=O)N(C)C1=O

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