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Product Information:

WEHI-539

WEHI-539 is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM.

Cat. No.: EX-A1595    Purity: >98%
WEHI-539
For research only, Do not use for Human!

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100mg595In-stock
250mgGet quoteIn-stock
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SynonymsCT-WE539
CAS No.1431866-33-9
Purity>98%
FormulaC31H29N5O3S2
Mol Weight583.724
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Lessene G, et al. Structure-guided design of a selective BCL-X(L) inhibitor. Nat Chem Biol. 2013 Jun;9(6):390-7.

[2]. Abed MN, et al. Antagonism of Bcl-XL is necessary for synergy between NSC 241240 and BH3 mimetics in ovarian cancer cells. J Ovarian Res. 2016 Apr 14;9:25.
CoACoA of WEHI-539
Smiles:NCC1=CC=C(OCCCC2=C(N=C(S2)C2=CC3=C(CCC\C3=N/NC3=NC4=CC=CC=C4S3)C=C2)C(O)=O)C=C1

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