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Product Information:

GSK872

GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM.

Cat. No.: EX-A1400    Purity: >98%
GSK872
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg370In-stock
250mg660In-stock
500mg870In-stock
1g1300In-stock


CAS No.1346546-69-7
Purity>98%
FormulaC19H17N3O2S2
Mol Weight383.487
Appearancewhite to off-white powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.
CoACoA of GSK872
Smiles:CC(C)S(=O)(=O)C1=CC=C2N=CC=C(NC3=CC=C4SC=NC4=C3)C2=C1

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