Product Information:
Cat. No.: EX-A1609 | Purity: >98% |
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CAS No. | 1338806-73-7 |
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Purity | >98% |
Formula | C33H34N4O3 |
Mol Weight | 534.6481 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Sampson PB, et al. The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1R,2S)-2-(3-((E)-4-(((cis)-2,6-Dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent. J Med Chem. 2015 Jan 8;58(1):147-69. http://dx.doi.org/10.1021/jm5005336
[2]. Mason JM, et al. Functional characterization of CFI-400945, a Polo-like kinase 4 inhibitor, as a potential anticancer agent. Cancer Cell. 2014 Aug 11;26(2):163-76. |
CoA | CoA of CFI-400945 |
Smiles: | COC1=CC2=C(NC(=O)[C@@]22C[C@H]2C2=CC=C3C(NN=C3\C=C\C3=CC=C(CN4C[C@H](C)O[C@H](C)C4)C=C3)=C2)C=C1 |
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