Product Information:
Cat. No.: EX-A845 | Purity: >98% |
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Synonyms | Volitinib |
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Synonyms 2 | AZD-6094 |
CAS No. | 1313725-88-0 |
Purity | >98% |
Formula | C17H15N9 |
Mol Weight | 345.3613 |
Appearance | Solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Jia H, et al. Discovery of (S)-1-(1-(Imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine (volitinib) as a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor in clinical development for treatment of cancer. J Med Chem. 2014 Sep 25;57(18):7577-89.
[2]. Gavine PR, et al. Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models. Mol Oncol. 2015 Jan;9(1):323-33. |
CoA | CoA of Savolitinib |
Smiles: | C[C@H](N1N=NC2=NC=C(N=C12)C1=CN(C)N=C1)C1=CN2C=CN=C2C=C1 |
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