Product Information:
Cat. No.: EX-A1051 | Purity: >98% |
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Synonyms | CDK 4/6 Inhibitor |
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Synonyms 2 | LEE011 analog |
CAS No. | 1256963-02-6 |
Purity | >98% |
Formula | C22H29ClN8 |
Mol Weight | 440.972 |
Appearance | Solid powder |
Solubility | DMSO > 50 mg/mL |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Cho YS, Borland M, Brain C, et al. 4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6. J Med Chem, 2010, 53(22): 7938-7957. |
CoA | CoA of CDK4-IN-1 |
Smiles: | CC(C)C1=NNC(Cl)=C1C1=NC(NC2=NC=C(C=C2)N2CCC(CC2)N(C)C)=NC=C1 |
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