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Product Information:

LGK-974

LGK974 (WNT974) is a selective and orally bioavailable porcupine (PORCN) inhibitor.

Cat. No.: EX-A1402    Purity: >98%
LGK-974
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg485In-stock
250mg665In-stock
500mg885In-stock
1g1385In-stock
5g4695In-stock
10g6950In-stock


SynonymsWNT-974
CAS No.1243244-14-5
Purity>98%
FormulaC23H20N6O
Mol Weight396.4445
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Liu J, et al. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20224-9.

CoACoA of LGK-974
Smiles:CC1=CC(=CC=N1)C1=NC=C(CC(=O)NC2=NC=C(C=C2)C2=CN=CC=N2)C=C1C

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