P7C3-A20

P7C3-A20 is a derivative of P7C3 with potent proneurogenic and neuroprotective activity. P7C3-A20 exerts an antidepressant-like effect. P7C3-A20 can cross the blood-brain barrier and therefore has the potential for brain injury treatment.


Cat. No.: EX-A373	Purity: >98%

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	695	In-stock
1g	895	In-stock
5g	2850	Inquire

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CAS No.	1235481-90-9
Purity	>98%
Formula	C22H19Br2FN2O
Mol Weight	506.205
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Junjie Bai, et al. The Small Molecule P7C3-A20 Exerts Neuroprotective Effects in a Hypoxic-Ischemic Encephalopathy Model via Activation of PI3K/AKT/GSK3β Signaling. Neuroscience. 2020 Jun 3;S0306-4522(20)30353-5. [2]. Blaya MO et al. Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury. J Neurotrauma. 2014 Mar 1;31(5):476-86. [3]. Walker AK et al. The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasinghippocampal neurogenesis. Mol Psychiatry. 2015 Apr;20(4):500-8.
CoA	CoA of P7C3-A20

Smiles:	COC1=CC(NCC(F)CN2C3=CC=C(Br)C=C3C3=C2C=CC(Br)=C3)=CC=C1


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