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Product Information:

PNU282987

PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM.

Cat. No.: EX-A1066    Purity: >98%
PNU282987
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg390In-stock
500mg580In-stock
1g850In-stock
2g1350In-stock
5g2550In-stock
10g3750In-stock


SynonymsPNU-282987 hydrochloride
CAS No.123464-89-1
Purity>98%
FormulaC14H18Cl2N2O
Mol Weight301.212
Appearancewhite to off-white powder
SolubilityDMSO >50 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Bodnar AL, et al. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem. 2005 Feb 24;48(4):905-8.

[2]. Dong Jun Yu, et al. Effect of ischemic preconditioning combined with α7 nAchR agonists on limb ischemia-reperfusion lung injury in rat. Biomed Res. 2017; Special Issue: ISSN 0970.
CoACoA of PNU282987
Smiles:Cl.ClC1=CC=C(C=C1)C(=O)N[C@H]1CN2CCC1CC2

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