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Product Information:

VE822

Berzosertib (VE-822) is an ATR inhibitor with a Ki value of less than 0.2 nM. It also inhibits ATM with a Ki of 34 nM.

Cat. No.: EX-A529    Purity: >98%
VE822
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg585In-stock
250mg785In-stock
500mg1085In-stock
1g1685In-stock
5g5855In-stock
10g8850In-stock


SynonymsBerzosertib
Synonyms 2VX-970
CAS No.1232416-25-9
Purity>98%
FormulaC24H25N5O3S
Mol Weight463.552
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Fokas E, et al. Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation. Cell Death Dis. 2012 Dec 6;3(12):e441.

[2]. Fokas E, et al. Targeting ATR in DNA damage response and cancer therapeutics. Cancer Treat Rev. 2014 Feb;40(1):109-17.
CoACoA of VE822
Smiles:CNCC1=CC=C(C=C1)C1=NOC(=C1)C1=NC(=CN=C1N)C1=CC=C(C=C1)S(=O)(=O)C(C)C

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