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Product Information:

RG-7388

RG-7388 (Idasanutlin) is a potent and selective MDM2 antagonist, inhibiting p53-MDM2 binding, with an IC50 of 6 nM.

Cat. No.: EX-A831    Purity: >98%
RG-7388
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
200mg550In-stock
500mg785In-stock
1g1085In-stock
5g3550In-stock
10g5685In-stock


SynonymsIdasanutlin
CAS No.1229705-06-9
Purity>98%
FormulaC31H29Cl2F2N3O4
Mol Weight616.482
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ding Q, et al. Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development. J Med Chem. 2013 Jul 25;56(14):5979-83.

CoACoA of RG-7388
Smiles:COC1=CC(=CC=C1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@](C#N)([C@H]1C1=CC=CC(Cl)=C1F)C1=CC=C(Cl)C=C1F)C(O)=O

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